Publications
2023
Hansen SG, Womack JL, Perez W, Schmidt KA, Marshall E, Iyer RF, Cleveland Rubeor H, Otero CE, Taher H, Vande Burgt NH, Barfield R, Randall KT, Morrow D, Hughes CM, Selseth AN, Gilbride RM, Ford JC, Caposio P, Tarantal AF, Chan C, Malouli D, Barry PA, Permar SR, Picker LJ, Früh K. Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV. JCI Insight. 2023 Mar 22;8(6):e164692. doi: 10.1172/jci.insight.164692. PMID: 36749635.
2022
Murdoch, D.M., Barfield, R., Chan, C. et al. Neuroimaging and immunological features of neurocognitive function related to substance use in people with HIV. J. Neurovirol. (2022). https://doi.org/10.1007/s13365-022-01102-2
Melissa J Harnois, Maria Dennis, Dagmar Stöhr, Sarah M Valencia, Nicole Rodgers, Eleanor C Semmes, Helen S Webster, Jennifer A Jenks, Richard Barfield, Justin Pollara, Cliburn Chan, Christian Sinzger, Sallie R Permar, Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus, The Journal of Infectious Diseases, Volume 226, Issue 9, 1 November 2022, Pages 1667–1677, https://doi.org/10.1093/infdis/jiac341
Chen JL, Fries CN, Berendam SJ, Rodgers NS, Roe EF, Wu Y, Li SH, Jain R, Watts B, Eudailey J, Barfield R, Chan C, Moody MA, Saunders KO, Pollara J, Permar SR, Collier JH, Fouda GG. Self-assembling peptide nanofiber HIV vaccine elicits robust vaccine-induced antibody functions and modulates Fc glycosylation. Sci Adv. 2022 Sep 23;8(38):eabq0273. doi: 10.1126/sciadv.abq0273. Epub 2022 Sep 23. PMID: 36149967; PMCID: PMC9506727.
Barfield, R., Qu, C., Steinfelder, R.S. et al. Association between germline variants and somatic mutations in colorectal cancer. Sci Rep 12, 10207 (2022). https://doi.org/10.1038/s41598-022-14408-2
Eckhoff AM, Connor AA, Thacker JKM, et al. A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery. Annals of Surgery. 2022 Jun;275(6):1094-1102. DOI: 10.1097/sla.0000000000005429. PMID: 35258509.
Barfield R, Huyghe JR, Lemire M, Dong X, Su YR, Brezina S, ..., Peters U, Hsu L. Genetic Regulation of DNA Methylation Yields Novel Discoveries in GWAS of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2022 May 4;31(5):1068-1076. doi: 10.1158/1055-9965.EPI-21-0724. PMID: 35247911; PMCID: PMC9081265.
2021
Fries, C.N., Chen, JL., Dennis, M.L. *et al.* HIV envelope antigen valency on peptide nanofibers modulates antibody magnitude and binding breadth. *Sci Rep* **11,** 14494 (2021). <https://doi.org/10.1038/s41598-021-93702-x>
Zhonghua Liu, Jincheng Shen, Richard Barfield, Joel Schwartz, Andrea A. Baccarelli & Xihong Lin (2021) Large-Scale Hypothesis Testing for Causal Mediation Effects with Applications in Genome-wide Epigenetic Studies, Journal of the American Statistical Association, DOI: 10.1080/01621459.2021.1914634
Huyghe JR, Harrison TA, Bien SA, et al Genetic architectures of proximal and distal colorectal cancer are partly distinct Gut Published Online First: 25 February 2021. doi: 10.1136/gutjnl-2020-321534
2020
Guptill, J.T., Barfield, R., Chan, C., et al. (2020), Reduced plasmablast frequency is associated with seronegative myasthenia gravis. Muscle & Nerve. Accepted Author Manuscript. <https://doi.org/10.1002/mus.27140>
Dong X, Su YR, Barfield R, Bien SA, He Q, et al. (2020) A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study. PLOS Genetics 16(8): e1008947. <https://doi.org/10.1371/journal.pgen.1008947>
Hidaka A, Harrison TA, Cao Y, et al. Intake of dietary fruit, vegetables, and fiber and risk of colorectal cancer according to molecular subtypes: A pooled analysis of 9 studies. Cancer Research. 2020; <doi:10.1158/0008-5472.CAN-20-0168>
Zaidi, S.H., Harrison, T.A., Phipps, A.I., et al. Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival. Nature Communications. 11, 3644 (2020).\</\>
2019
Barfield R, Wang H, Liu Y, …, Lin X, Redline S, Sofer T. Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations. Sleep. May 2019.
Cade BE, Chen H, Stilp AM, Louie T, Ancoli-Israel S, Arens R, Barfield R ,..., Lin, X, Redline, S. Associations of variants in the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep. PLOS Genetics. April 2019.
2018
J. Carmona, R. Barfield\*, T. Panni, ..., H. Schulz, and A. Baccarelli, Metastable DNA methylation sites associated with longitudinal lung function decline and aging in humans: an epigenome-wide study in the NAS and KORA cohorts. Epigenetics. October 2018.
Barfield R , Feng H, Gusev A, et al. Transcriptome‐wide association studies accounting for colocalization using Egger regression. Genetic Epidemiology 2018; 1–16.
Wu L, Shi W, Long J, Guo X, Michailidou K, Beesley J, Bolla MK, Shu X-O, Lu Y, Cai Q,..., Barfield R,..., Zheng W. 2018. A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nature Genetics.
2017
Barfield R\*, Shen J, Just AC, et al. Testing for the indirect effect under the null for genome‐wide mediation analyses. Genetic Epidemiology, 2017;41:824–833.
2016
Krier J, Barfield R\*, Green RC, Kraft P. Reclassification of genetic-based risk predictions as GWAS data accumulate. Genome Medicine. 2016;8:20.
2014
Barfield, R. T., Almli, L. M., Kilaru, V. , Smith, A. K., Mercer, K. B., Duncan, R. , Klengel, T. , Mehta, D. , Binder, E. B., Epstein, M. P., Ressler, K. J. and Conneely, K. N. (2014), Accounting for Population Stratification in DNA Methylation Studies. Genetic Epidemiology, 38: 231-241.
Wolpin, B. M., Rizzato, C., Kraft, P., Kooperberg, C., Petersen, G. M., Wang, Z.,..,Barfield R,..., Amundadottir, L. T. (2014). Genome-wide association study identifies multiple susceptibility locifor pancreatic cancer. Nature Genetics, 46(9), 994–1000.
2013
Goldlust IS, Hermetz KE, Catalano LM, Barfield R , et al. Mouse model implicates GNB3 duplication in a childhood obesity syndrome. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(37):14990-14994.
2012
Barfield, R., Kilaru, V., Smith, A. K. & Conneely, K. N. (2012). CpGassoc: an R function for analysis of DNA methylation microarray data. Bioinformatics, 28, 1280-1281. doi: 10.1093/bioinformatics/bts124
Mercer KB, Orcutt HK, Quinn JF, Fitzgerald C, Conneely K, Barfield R, Gillespie C, Ressler K. Acute and Posttraumatic Stress Symptoms in a Prospective Gene × Environment Study of a University Campus Shooting. Arch Gen Psychiatry. 2012;69(1):89–97.
Kilaru V, Barfield R, Schroeder JW, Smith AK, Conneely KN (2012). MethLAB: A graphical user interface package for the analysis of array-based DNA methylation data. Epigenetics, 7:3, 225-229.
\* Co First Author